Concentration Domain
Nanomolar to Micromolar (nM to µM) Concentration Conversion
In pharmacology, biochemistry, and receptor-ligand binding kinetics, nanomolar ($10^{-9}\text{ M}$) and micromolar ($10^{-6}\text{ M}$) concentrations quantify drug affinity ($K_d, IC_{50}$) and enzyme saturation.
Conversion Formula
µM = nM ÷ 1,000 | µM = nM × 0.001
nM = µM × 1,000
Biochemical Affinity Ranges
| Nanomolar (nM) | Micromolar (µM) | Affinity Classification ($K_d$) | Biological Example |
|---|---|---|---|
| 0.1–10 nM | 0.0001–0.01 µM | High Affinity (Picomolar–Low Nanomolar) | Monoclonal Antibody Binding |
| 10–500 nM | 0.01–0.5 µM | Moderate High Affinity | Target Drug Receptor Antagonist |
| 1,000 nM | 1.0 µM | Moderate Affinity ($1\text{ µM}$ Threshold) | Enzyme-Substrate Complex |
| 10,000+ nM | 10.0+ µM | Weak Affinity | Non-specific Protein Association |